mgr inż. Vitaliy Atamaniuk
The topic of my dissertation is “Development of the magnetic resonance elastography technique for measuring the stiffness and viscosity of human organs.”
My main field of interest is the development of the Magnetic Resonance Elastography (MRE) technique. MRE is a relatively new imaging technique that can assess the stiffness of the soft tissue, which makes it very sensitive to any pathological changes in the organ.
My goal is to make it work even better by increasing the examinations’ quality, automating the analysis of the images, and gathering more information about the normative values of the stiffness in the local population.
Since 2018, together with the University of Rzeszow’s MR elastography group, I have been working on the following topics:
- Evaluation of normative liver stiffness values for healthy volunteers;
- Assessment of Liver Iron Concentration (LIC) values in healthy volunteers using MRI and determination of the correlation between liver iron concentration and liver stiffness in healthy volunteers;
- Evaluation of the normative spleen stiffness values for the healthy Caucasian population;
- Investigation of the effects of meal intake on the liver and spleen stiffness values in healthy volunteers;
- MRE examinations of the uterus in patients with uterine leiomyomas;
- MRE examinations of numerous patients with non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease (ALD), Autoimmune hepatitis (AIH), Hepatitis B, and Hepatitis C.
The results of these research works allow for a better understanding of the MRE technique and complement the existing knowledge on the specific features of human anatomy that can be evaluated using the MRE technique.
My future plans include:
- Performing liver and spleen MRE examinations in patients with esophageal varices;
- Installing 3D MRE in order to perform examinations of small organs, including pancreas, uterus, and others;
- Using Artificial Intelligence and machine learning to improve the quality of MRE exams (noise and motion artifacts reduction, automated stiffness measurement, and so on);
- Developing our own passive drivers of different shapes for better adhering to the patients’ body;
- Performing MRE examinations of the brain in healthy volunteers and sick patients (for example, with SM).
The achievement of these goals will be a great step towards a better understanding of our bodies. Moreover, MR elastography has an insane potential to become the most efficient imaging technique when it comes to the diagnosis of chronic liver diseases and many other sicknesses, so it is crucial to continually develop it. And that is what I am currently doing!
- Kołodziej, D. Jesionek-Kupnicka, M. Braun, V. Atamaniuk, J. Cebulski, M. Cholewa, S. Słoniec, J. Kopczyński, P. Herauld, M. Tobin, J. Vongsvivut, I. Zawlik, Discrimination of aggressive and classic subtypes variants of mantle cell lymphomas using synchrotron-FTIR microspectroscopy, Scientific Reports, 9 (2019) 12857, (Web of Science Citation – 4 ; Impact factor – 4.011; MNiSW = 140, DOI – 10.1038/s41598-019-49326-3)
- Obrzut, V. Atamaniuk, B. Obrzut, R. Ehman, M. Cholewa, M. Rzucidło, A. Pozaruk, K.Gutkowski, Normative values for magnetic resonance elastography-based liver stiffness in a healthy population, Polish Archives of Internal Medicine, Vol. 129, No. 4 (2019): 242-252, (Web Of Science Citation – 3 ; Impact factor – 3.007; MNiSW = 100, DOI - 10.20452/pamw.4478)
- Obrzut, V. Atamaniuk, KJ. Glaser, J. Chen, RL. Ehman, B. Obrzut, M. Cholewa, K. Gutkowski, Value of liver iron concentration in healthy volunteers assessed by MRI, Scientific Reports, 10 (2020) 17887, (Citation – 2; Impact factor – 4.379; MNiSW = 140, DOI - 10.1038/s41598-020-74968-z)
- Obrzut,V. Atamaniuk, J. Chen, B. Obrzut, RL. Ehman, M. Cholewa, A. Palusińska, K. Gutkowski, Postprandial hepatic stiffness changes on magnetic resonance elastography in healthy volunteers, Scientific Reports, (2021) Accepted for publication, (Citation – ; Impact factor (2020) – 4.379; MNiSW = 140, DOI - 10.1038/s41598-021-99243-7)
- Australian Synchrotron, Melbourne, 08.2018 – 11.2018, Beamline Scientist, IR Beamline - During 10-weeks internship at the Australian Synchrotron IR Beamline, I have been working on the FTIR spectroscopy of mantle cell lymphoma and the analysis of the results (PCA, HCA).
- Grant 25 / NAWA-PROM-UR / 2019, Polish National Agency for Academic Exchange. Grant for a 4-week visit to Mayo Clinic, Rochester, MN, USA. PLN 16,000.