2021 r.

Friedenreich Christine M., Franco Eduardo, Baran Joanna, Czenczek-Lewandowska Ewelina, Dereń Katarzyna, Łuszczki Edyta, Mazur Artur, Sobek Grzegorz, Weres Aneta, "Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight" [w:]eLife, 2021, nr 10, id. art. e60060, p-ISSN: 2050-084X, 200 pkt.


From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions.

Melnyk Natalia, Pawłowska Karolina A., Ziaja Maria, Wojnowski Wojciech, Koshovyi Oleh, Granica Sebastian, Bazylko Agnieszka, "Characterization of herbal teas containing lime flowers - Tiliae flos by HPTLC method with chemometric analysis" [w:] Food Chemistry, 2021 : Vol. 346, id. art. 128929, p-ISSN: 0308-8146,e-ISSN: 1873-7072, 200 pkt.


Linden trees are a source of food products called lime flowers (Tiliae flos), traditionally used in the form of infusion for the treatment of feverish colds and coughs. Lime flowers should include flowers of Tilia cordata Mill, T.x europaea L., and T. platyphyllos Scop. or a mixture of these. The aim of current research was to establish a fast, sensitive HPTLC (high-performance thin-layer chromatography) method that would allow the differentiation of material obtained from five species of lime occurring in Europe. The fingerprints for distinguishing these species were established, as well as a key for identification based on a visual evaluation of chromatograms. The results obtained were also subjected to chemometric analyses. It was shown that each species contains characteristic compounds i.e. linarin that can be used for their identification. The method developed can, in theory, be introduced for the quality control or authentication of linden flowers on the European market.

Spychaj Radosław, Kucharska Alicja Z., Szumny Antoni, Przybylska Dominika, Pejcz Ewa, Piórecki Narcyz, "Potential valorization of Cornelian cherry (Cornus mas L.) stones : Roasting and extraction of bioactive and volatile compounds"[w:] Food Chemistry,  2021 : Vol. 358, id. art. 129802, p-ISSN: 0308-8146, e-ISSN: 1873-7072, 200 pkt.


This study aimed to characterize the antioxidant potential, bioactive and volatile compounds of the stones from fruits of Cornus mas. Both fresh and roasted stones show a high antioxidant potential (166.48-509.74 μmol TE/g dw stones), which significantly depends on the cultivars. The roasted stones preserved 43.6% (DPPH; 'Raciborski') to 97.2% (FRAP; 'Alesha') of the antioxidant activity of the non-roasted stones. In the stones, two iridoids and ellagic acid were determined. During roasting, loganic acid remained stable, whereas cornuside was completely degraded. The analyses showed a 30-fold increase in the concentration of ellagic acid and in the formation of two of its derivatives. The major aroma compound of the roasted stones was furfural, but we also identified 18 pyrazine derivatives. This study is the first attempt to valorize Cornelian cherry stones via roasting. The roasted stones can be a coffee substitute, or aromatic and bioactive additions to cereal coffees.

Zhou Bin, Carrillo-Larco Rodrigo M., Danaei Goodarz, Riley Leanne M., Paciorek Christopher J., Stevens Gretchen A., Gregg Edward W., Bennett James E., Solomon Bethlehem D., Baran Joanna, Bartosiewicz Anna, Łuszczki Edyta, Matłosz Piotr, Weres Aneta, Wyszyńska Justyna, "Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019 : a pooled analysis of 1201 population-representative studies with 104 million participants" The Lancet, 2021 : Vol. 398, nr 10304, p. 957-980,p-ISSN: 0140-6736, 200 pkt.


Hypertension  can  be  detected  at  the  primary  health-care  level  and  low-cost  treatments  can  effectively  control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories.

Brian G Feagan, Silvio Danese, Edward V Loftus Jr, Séverine Vermeire, Stefan Schreiber, Timothy Ritter, Ronald Fogel, Rajiv Mehta, Sandeep Nijhawan, Radosław Kempiński, Rafał Filip, Ihor Hospodarskyy, Ursula Seidler, Frank Seibold, Ian L P Beales, Hyo Jong Kim, John McNally, Chohee Yun, Sally Zhao, Xiaopeng Liu, Chia-Hsiang Hsueh, Chantal Tasset, Robin Besuyen, Mamoru Watanabe, William J Sandborn, Gerhard Rogler, Toshifumi Hibi, Laurent Peyrin-Biroulet "Filgotinib as induction and maintenance therapy for ulcerative colitis (SELECTION): a phase 2b/3 double-blind, randomised, placebo-controlled trial", Lancet 2021; 397: 2372–84, p-ISSN: 0140-6736, 200 pkt.


The global prevalence of ulcerative colitis is increasing, and induction and maintenance of remission is a crucial therapeutic goal. We assessed the efficacy and safety of filgotinib, a once-daily, oral Janus kinase 1 preferential inhibitor, for treatment of ulcerative coliti